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WTF- Chemical Imbalance-Depression Model is an outmoded way of thinking?!

Hi,
When It Comes To Depression, Serotonin Isn't The Whole Story 
Snip:

But for many scientists who research depression, this explanation is no longer satisfying.

 

"Chemical imbalance is sort of last-century thinking. It's much more complicated than that," says Dr. Joseph Coyle, a professor of neuroscience at Harvard Medical School. "It's really an outmoded way of thinking."

Coyle, who is also the editor of the journal Archives of General Psychiatry, says that though serotonin plays a role in depression, low serotonin is likely not the cause of depression. Scientific thinking has clearly shifted, he says.

Still, the story of serotonin remains. Why does it continue to have such a powerful grip on the popular imagination?

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Comment: Any one else wonder if the huge profits generated by the serotonin-story have anything to do with the story's longevity?
Snip:

This had less to do with the efficacy of Prozac (it is not better at treating depression than tricyclics, the earlier generation of antidepressants) than with the fact that the drug had relatively few side effects.

"It was very free of side effects," says Pedro Delgado. "And so it began to be used very widely, and there was a lot of enthusiasm for it."

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Comment: The common adverse effects of Prozac like: anxiety, headaches, nausea, diarrhea, insomnia, decreased appetite and sex drive and sexual impairment were relatively a lot better than the adverse effects of the tricyclic treatments so Prozac became the drug of choice...
Geez...
Snip:
Delgado also makes this argument. In the 1990s, he carried out a study that showed that if you take a normal person and deplete them of serotonin, they will not become depressed. He says he feels this demonstrates that low serotonin doesn't cause depression.
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Comment: That works for me -- If a person does not become depressed after being depleted of serotonin - I'd say we need to go back to the drawing board.
Your opinions are welcome:
Full item and iterview here:
When It Comes To Depression, Serotonin Isn't The Whole Story : Shots - Health Blog : NPR

http://www.npr.org/blogs/health/2012/01/23/145525853/when-it-comes-...

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The following video, illustrating that the "right," rather than the proper psychiatric diagnosis and medication, may often be better answer to improving learning for children and adults. It has been viewed on You Tube by over eight million people. As James Malone has stated, "I would suggest that anyone pondering public education or Big Pharma remember the edit 'follow the money.'"

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